Summaries of Studies, Doyle Stulting and Stulting Research Center

What is a clinical trial?

Clinical trials are research studies that test the safety and effectiveness of new medical interventions in people. Clinical trials are essential for developing new and better ways to prevent, diagnose, and treat diseases. They are also used to improve the quality of life for people with chronic conditions.

Clinical trials are carefully regulated to protect the safety of participants. All clinical trials must be approved by an institutional review board (IRB), which is a committee of experts that reviews the study protocol to make sure it is ethical and safe.

Participants in clinical trials must also provide informed consent, which means that they understand the risks and benefits of participating in the trial and agree to participate voluntarily.

The Stulting Research Center at Woolfson Eye Institute

The Stulting Research Center at Woolfson Eye Institute is an independent research organization currently conducting several FDA clinical trials and independent studies. To learn more about Dr. Stulting, click here.

See below for more information on our clinical studies, or use the search tool below to search by specialty.

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Topography Guided Custom Ablation Treatment

Dr. Stulting was looking for methods for improving the vision of patients who had undergone LASIK and similar vision correction procedures.  His goal was to assist laser manufacturers in designing hardware and software to optimize the optical properties of corneas of patients who had irregularities induced by such procedures.  Dr. Stulting was Medical Monitor for FDA clinical trials that showed the technology was very successful for new LASIK cases. In fact, many  patients in the FDA trial had better vision without glasses than they had with glasses prior to the surgery. The technology has also been used to repair irregular corneas.


Brillouin Microscopy

Dr. Stulting has studied corneal biomechanics for many years, and served as a consultant for a company looking to provide an instrument that could reliably assess these properties for clinical purposes.  Brillouin microscopy uses a low-power near-infrared laser beam to determine corneal biomechanical properties, which can help surgeons to make better decisions about such things as determining candidacy for LASIK, as well as for monitoring the success of procedures such as corneal crosslinking.  In his abstract published by the Association for Research in Vision and Ophthalmology, Dr. Stulting wrote, “Brillouin microscopy is capable of detecting the corneal stiffening effect soon after a corneal crosslinking procedure that has been shown to increase vision and reduce the corneal curvature of corneas with keratoconus.”


Corneal Crosslinking

Corneal crosslinking is a method of stiffening the cornea to prevent progression of keratoconus and corneal ectasia. First performed by Dr. Theo Seiler in Dresden, Germany, it has become the treatment of choice for these diseases, dramatically reducing the number of corneal transplants performed for the treatment of these diseases. Dr. Stulting first learned about this procedure about 20 years ago when he was Editor-In-Chief of the journal Cornea. Recognizing its importance, he initiated an FDA clinical trial and was the first to perform the procedure in the United States in 2008.

Dr. Stulting brought his crosslinking studies to Woolfson Eye in 2010 and has continued to oversee subsequent studies developing less invasive methods for providing this valuable treatment to patients in need of corneal strengthening to stabilize their vision and help prevent the need for corneal transplantation.

Iris Defects


Artificial Iris

Dr. Stulting served as a consultant for the FDA study on the safety and efficacy of the artificial iris for patients with light sensitivity related to iris defects.  The product ultimately was approved by the FDA for the treatment of symptoms and an unacceptable cosmetic appearance created by iris defects.

Age-Related Macular Degeneration


Implantable Miniature Telescope (IMT)

Dr. Stulting was a consultant to the company developing the implantable miniature telescope. This is an implantable device that provides high magnification of a patient’s surroundings like a hand-held telescope would provide.  It allows patients with bilateral, end-stage, age-related macular degeneration (AMD) to see details that would not otherwise be visible to them. The researchers found that the IMT improves functional vision in this population with extremely severe visual loss and no other available treatments.

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